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Pipeline

Reglagene is Transforming Tubulin Therapies for CNS Diseases by discovering and developing novel therapies 

RGN6024 - Anti-Cancer

Microtubule Targeting Agent

RGN6024 is a potent, orally administered, blood-brain barrier penetrant therapy that has been optimized for the treatment of high-grade gliomas, such as glioblastoma as well as brain metastases from breast, lung, and melanoma cancers.

Development

Approach

Lead Optimization

IND-Enabling

Phase I/IB

Monotherapy

Combination with Radiation

Combination with TMZ

High-Grade Glioma & Glioblastoma

High-Grade Glioma & Glioblastoma

Breast, Lung, & Melanoma Cancer

High-Grade Glioma & Glioblastoma

RGNXXX1 - Anti-Infectivity & Anti-Inflammation

Microtubule Targeting Agent

RGNXXX1 is a potent, orally administered, blood-brain barrier penetrant therapy that is being optimized for the treatment of anti-infectivity and neuro-inflammation, such as acute COVID-19 and neuro-inflammatory diseases, respectfully.

IND-Enabling

Development

Approach

Lead Optimization

Phase I/IB

Anti-Infectivity

Anti-Inflammation

Acute COVID-19

Neuro-Inflammatory Diseases

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